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1

Oxygen Toxicity in Premature Infants

Barry Weinberger, Debra L. Laskin, Diane E. Heck, Jeffrey D. Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

2002

Language:

english

File:

PDF, 65 KB

english, 2002

2

Macrophages and Tissue Injury: Agents of Defense or Destruction?

Laskin, Debra L., Sunil, Vasanthi R., Gardner, Carol R., Laskin, Jeffrey D.

Journal:

Annual Review of Pharmacology

Year:

2011

Language:

english

File:

PDF, 364 KB

english, 2011

3

Isolation and Partial Characterization of Subpopulations of Alveolar Macrophages, Granulocytes, and Highly Enriched Interstitial Macrophages from Rat Lung

Lavnikova, Natasha, Prokhorova, Svetlana, Helyar, Lesley, Laskin, Debra L.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

1993

Language:

english

File:

PDF, 1.01 MB

english, 1993

4

Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase

Szilagyi, John T., Fussell, Karma C., Wang, Yun, Jan, Yi-Hua, Mishin, Vladimir, Richardson, Jason R., Heck, Diane E., Yang, Shaojun, Aleksunes, Lauren M., Laskin, Debra L., Laskin, Jeffrey D.

Journal:

Toxicology and Applied Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.64 MB

english, 2018

5

NETs: a new biomarker of traffic-related air pollution exposure: are they ready to catch fish?

Kipen, Howard M, Laskin, Debra L.

Journal:

European Respiratory Journal

Year:

2020

File:

PDF, 293 KB

2020

6

Characterization of the inflammatory response to biomaterials using a rodent air pouch model

Kimberly A. Hooper, Thomas L. Nickolas, Edward J. Yurkow, Joachim Kohn, Debra L. Laskin

Journal:

Journal of Biomedical Materials Research Part B: Applied Biomaterials

Year:

2000

Language:

english

File:

PDF, 637 KB

english, 2000

7

Cytostasis is required for IL-1 induced nitric oxide production in transformed hamster fibroblasts

Natasha Lavnikova, Anand Lakhotia, Naimish Patel, Svetlana Prokhorova, Debra L. Laskin

Journal:

Journal of Cellular Physiology

Year:

1996

Language:

english

File:

PDF, 688 KB

english, 1996

8

Activation of liver macrophages following phenobarbital treatment of rats

Debra L. Laskin, Fredika M. Robertson, Anne M. Pilaro, Jeffrey D. Laskin

Journal:

Year:

1988

Language:

english

File:

PDF, 634 KB

english, 1988

9

Changes in sulfated proteoglycan production after activation of rat liver macrophages

Jeffrey D. Laskin, Anthea Dokidis, Carol R. Gardner, Debra L. Laskin

Journal:

Year:

1991

Language:

english

File:

PDF, 805 KB

english, 1991

10

Liver macrophage-mediated cytotoxicity toward mastocytoma cells involves phagocytosis of tumor targets

Carol R. Gardner, Arthur J. Wasserman, Dr. Debra L. Laskin

Journal:

Year:

1991

Language:

english

File:

PDF, 895 KB

english, 1991

11

Lipopolysaccharide treatment of rats alters antigen expression and oxidative metabolism in hepatic macrophages and endothelial cells

Thomas W. Mc Closkey, Jeanine A. Todaro, Dr. Debra L. Laskin

Journal:

Year:

1992

Language:

english

File:

PDF, 1.36 MB

english, 1992

12

Induction of hepatic ito cell nitric oxide production after acute endotoxemia

Lesley Helyar, Daniela S. Bundschuh, Jeffrey D. Laskin, Debra L. Laskin

Journal:

Year:

1994

Language:

english

File:

PDF, 864 KB

english, 1994

13

Modulation of macrophage functioning abrogates the acute hepatotoxicity of acetaminophen

Debra L. Laskin, Carol R. Gardner, Veronica F. Price, David J. Jollow

Journal:

Year:

1995

Language:

english

File:

PDF, 878 KB

english, 1995

14

Hepatic nitric oxide production following acute endotoxemia in rats is mediated by increased inducible nitric oxide synthase gene expression

Debra L. Laskin, Marina Rodriguez Del Valle, Diane E. Heck, Shaw-Min Hwang, S. Tsuyoshi Ohnishi, Stephen K. Durham, Nancy L. Goller, Dr Jeffrey D. Laskin

Journal:

Year:

1995

Language:

english

File:

PDF, 1.43 MB

english, 1995

15

Role of nitric oxide in acetaminophen-induced hepatotoxicity in the rat

Carol R. Gardner, Diane E. Heck, Chung S. Yang, Paul E. Thomas, Xu-Jie Zhang, George L. DeGeorge, Jeffrey D. Laskin, Debra L. Laskin

Journal:

Year:

1998

Language:

english

File:

PDF, 199 KB

english, 1998

16

Inhibition of macrophages with gadolinium chloride alters intercellular adhesion molecule-1 expression in the liver during acute endotoxemia in rats

Nosheen Ahmad, Carol R. Gardner, Edward J. Yurkow, Debra L. Laskin

Journal:

Year:

1999

Language:

english

File:

PDF, 537 KB

english, 1999

17

Acute endotoxemia prolongs the survival of rat lung neutrophils in response to 12-O-tetradecanoyl-phorbol 13-acetate

Vasanthi R. Sunil, Agnieszka J. Connor, Natasha Lavnikova, Carol R. Gardner, Jeffrey D. Laskin, Debra L. Laskin

Journal:

Journal of Cellular Physiology

Year:

2002

Language:

english

File:

PDF, 201 KB

english, 2002

18

Fluorescence assay for per-cell estimation of cytochrome P-450-dependent monooxygenase activities in keratinocyte suspensions and cultures

John J. Reiners Jr., Amador R. Cantu, Amy Pavone, Stephanie C. Smith, Carol R. Gardner, Debra L. Laskin

Journal:

Analytical Biochemistry

Year:

1990

Language:

english

File:

PDF, 929 KB

english, 1990

19

Enhanced passive pulmonary targeting and retention of PEGylated rigid microparticles in rats

Hilliard L. Kutscher, Piyun Chao, Manjeet Deshmukh, Sujata Sundara Rajan, Yashveer Singh, Peidi Hu, Laurie B. Joseph, Stanley Stein, Debra L. Laskin, Patrick J. Sinko

Journal:

International Journal of Pharmaceutics

Year:

2010

Language:

english

File:

PDF, 609 KB

english, 2010

20

Role of macrophages and inflammatory mediators in chemically induced toxicity

Debra L. Laskin, Jeffrey D. Laskin

Journal:

Year:

2001

Language:

english

File:

PDF, 105 KB

english, 2001

21

Oxidants and antioxidants in sulfur mustard–induced injury

Jeffrey D. Laskin, Adrienne T. Black, Yi-Hua Jan, Patrick J. Sinko, Ned D. Heindel, Vasanthi Sunil, Diane E. Heck, Debra L. Laskin

Journal:

Annals of the New York Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 154 KB

english, 2010

22

Macrophages, reactive nitrogen species, and lung injury

Debra L. Laskin, Vasanthi R. Sunil, Ladan Fakhrzadeh, Angela Groves, Andrew J. Gow, Jeffrey D. Laskin

Journal:

Annals of the New York Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 159 KB

english, 2010

23

IFN-γ-Mediated Inhibition of COX-2 Expression in the Placenta from Term and Preterm Labor Pregnancies

Nazeeh Hanna, Lea Bonifacio, Pradeep Reddy, Iman Hanna, Barry Weinberger, Shaun Murphy, Debra Laskin, Surendra Sharma

Journal:

American Journal of Reproductive Immunology

Year:

2004

Language:

english

File:

PDF, 292 KB

english, 2004

24

Upregulation of phosphoinositide 3-kinase and protein kinase B in alveolar macrophages following ozone inhalation. Role of NF-κB and STAT-1 in ozone-induced nitric oxide production and toxicity

Debra L. Laskin, Ladan Fakhrzadeh, Diane E. Heck, Donald Gerecke, Jeffrey D. Laskin

Journal:

Molecular and Cellular Biochemistry

Year:

2002

Language:

english

File:

PDF, 105 KB

english, 2002

25

Drug-induced liver injury: Mechanisms and test systems

D.Montgomery Bissell, Gregory J. Gores, Debra L. Laskin, Jay H. Hoofnagle

Journal:

Year:

2001

Language:

english

File:

PDF, 123 KB

english, 2001

26

Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse

Donna M. Dambach, Linda M. Watson, Kevin R. Gray, Stephen K. Durham, Debra L. Laskin

Journal:

Year:

2002

Language:

english

File:

PDF, 437 KB

english, 2002

27

Distinct Roles of Tumor Necrosis Factor-α and Nitric Oxide in Acute Liver Injury Induced by Carbon Tetrachloride in Mice

Lisa A. Morio, Hawjyh Chiu, Karen A. Sprowles, Peihong Zhou, Diane E. Heck, Marion K. Gordon, Debra L. Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

2001

Language:

english

File:

PDF, 230 KB

english, 2001

28

Tissue Injury Following Inhalation of Fine Particulate Matter and Hydrogen Peroxide Is Associated with Altered Production of Inflammatory Mediators and Antioxidants by Alveolar Macrophages

Lisa A. Morio, Kimberly A. Hooper, Jennie Brittingham, Tsung-Hung Li, Ronald E. Gordon, Barbara J. Turpin, Debra L. Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

2001

Language:

english

File:

PDF, 427 KB

english, 2001

29

Differential Induction of Heme Oxygenase-1 in Macrophages and Hepatocytes during Acetaminophen-Induced Hepatotoxicity in the Rat: Effects of Hemin and Biliverdin

Hawjyh Chiu, Jennie A. Brittingham, Debra L. Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

2002

Language:

english

File:

PDF, 828 KB

english, 2002

30

Reduced Hepatotoxicity of Acetaminophen in Mice Lacking Inducible Nitric Oxide Synthase: Potential Role of Tumor Necrosis Factor-α and Interleukin-10

Carol R. Gardner, Jeffrey D. Laskin, Donna M. Dambach, Michael Sacco, Stephen K. Durham, Mary K. Bruno, Steven D. Cohen, Marion K. Gordon, Donald R. Gerecke, Peihong Zhou, Debra L. Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

2002

Language:

english

File:

PDF, 629 KB

english, 2002

31

Potential role of activated macrophages in acetaminophen hepatotoxicity: II. Mechanism of macrophage accumulation and activation

Debra L. Laskin, Anne M. Pilaro, Sungchul Ji

Journal:

Toxicology and Applied Pharmacology

Year:

1986

Language:

english

File:

PDF, 997 KB

english, 1986

32

Potential role of activated macrophages in acetaminophen hepatotoxicity: I. Isolation and characterization of activated macrophages from rat liver

Debra L. Laskin, Anne M. Pilaro

Journal:

Toxicology and Applied Pharmacology

Year:

1986

Language:

english

File:

PDF, 5.78 MB

english, 1986

33

Increased production of tumor necrosis factor-α by bone marrow leukocytes following benzene treatment of mice

Laureen MacEachern, Debra L. Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

1992

Language:

english

File:

PDF, 926 KB

english, 1992

34

Alterations in the morphology and functional activity of bone marrow phagocytes following benzene treatment of mice

Laureen MacEachern, Robert Snyder, Debra L. Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.86 MB

english, 1992

35

Distinct patterns of sulfated proteoglycan biosynthesis in human monocytes, granulocytes and myeloid leukemic cells

Jeffrey D. Laskin, Anthea Dokidis, Andrea A. Sirak, Debra L. Laskin

Journal:

Leukemia Research

Year:

1991

Language:

english

File:

PDF, 913 KB

english, 1991

36

Inhibition of interferon-γ signaling by a mercurio-substituted dihydropsoralen in murine keratinocytes

Christine A. Martey, Anna M. Vetrano, Marilyn S. Whittemore, Thomas M. Mariano, Diane E. Heck, Debra L. Laskin, Ned D. Heindel, Jeffrey D. Laskin

Journal:

Biochemical Pharmacology

Year:

2005

Language:

english

File:

PDF, 298 KB

english, 2005

37

UVB light regulates expression of antioxidants and inflammatory mediators in human corneal epithelial cells

Adrienne T. Black, Marion. K. Gordon, Diane E. Heck, Michael A. Gallo, Debra L. Laskin, Jeffrey D. Laskin

Journal:

Biochemical Pharmacology

Year:

2011

Language:

english

File:

PDF, 433 KB

english, 2011

38

Role of cytochrome P450 reductase in nitrofurantoin-induced redox cycling and cytotoxicity

Yun Wang, Joshua P. Gray, Vladimir Mishin, Diane E. Heck, Debra L. Laskin, Jeffrey D. Laskin

Journal:

Free Radical Biology and Medicine

Year:

2008

Language:

english

File:

PDF, 825 KB

english, 2008

39

Application of the Amplex red/horseradish peroxidase assay to measure hydrogen peroxide generation by recombinant microsomal enzymes

Vladimir Mishin, Joshua P. Gray, Diane E. Heck, Debra L. Laskin, Jeffrey D. Laskin

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 532 KB

english, 2010

40

Threshold size for optimal passive pulmonary targeting and retention of rigid microparticles in rats

Hilliard L. Kutscher, Piyun Chao, Manjeet Deshmukh, Yashveer Singh, Peidi Hu, Laurie B. Joseph, David C. Reimer, Stanley Stein, Debra L. Laskin, Patrick J. Sinko

Journal:

Journal of Controlled Release

Year:

2010

Language:

english

File:

PDF, 1.05 MB

english, 2010

41

Role of tumor necrosis factor receptor 1 (p55) in hepatocyte proliferation during acetaminophen-induced toxicity in mice

Hawjyh Chiu, Carol R Gardner, Donna M Dambach, Stephen K Durham, Jennie A Brittingham, Jeffrey D Laskin, Debra L Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

2003

Language:

english

File:

PDF, 619 KB

english, 2003

42

Distinct roles of NF-κB p50 in the regulation of acetaminophen-induced inflammatory mediator production and hepatotoxicity

Donna M. Dambach, Stephen K. Durham, Jeffrey D. Laskin, Debra L. Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 450 KB

english, 2006

43

Pulmonary effects of inhaled limonene ozone reaction products in elderly rats

Vasanthi R. Sunil, Robert J. Laumbach, Kinal J. Patel, Barbara J. Turpin, Ho-Jin Lim, Howard M. Kipen, Jeffrey D. Laskin, Debra L. Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

2007

Language:

english

File:

PDF, 3.02 MB

english, 2007

44

Regulation of caveolin-1 expression, nitric oxide production and tissue injury by tumor necrosis factor-α following ozone inhalation

Ladan Fakhrzadeh, Jeffrey D. Laskin, Debra L. Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

2008

Language:

english

File:

PDF, 1.17 MB

english, 2008

45

UVB light upregulates prostaglandin synthases and prostaglandin receptors in mouse keratinocytes

Adrienne T. Black, Joshua P. Gray, Michael P. Shakarjian, Vladimir Mishin, Debra L. Laskin, Diane E. Heck, Jeffrey D. Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

2008

Language:

english

File:

PDF, 1.25 MB

english, 2008

46

Increased oxidative stress and antioxidant expression in mouse keratinocytes following exposure to paraquat

Adrienne T. Black, Joshua P. Gray, Michael P. Shakarjian, Debra L. Laskin, Diane E. Heck, Jeffrey D. Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

2008

Language:

english

File:

PDF, 490 KB

english, 2008

47

Potential role of caveolin-1 in acetaminophen-induced hepatotoxicity

Carol R. Gardner, Joshua P. Gray, Laurie B. Joseph, Jessica Cervelli, Nicole Bremer, Yunjung Kim, Vladimir Mishin, Jeffrey D. Laskin, Debra L. Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

2010

Language:

english

File:

PDF, 2.49 MB

english, 2010

48

Inflammatory effects of inhaled sulfur mustard in rat lung

Rama Malaviya, Vasanthi R. Sunil, Jessica Cervelli, Dana R. Anderson, Wesley W. Holmes, Michele L. Conti, Ronald E. Gordon, Jeffrey D. Laskin, Debra L. Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.86 MB

english, 2010

49

Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide

Adrienne T. Black, Laurie B. Joseph, Robert P. Casillas, Diane E. Heck, Donald R. Gerecke, Patrick J. Sinko, Debra L. Laskin, Jeffrey D. Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

2010

Language:

english

File:

PDF, 841 KB

english, 2010

50

Inhibition of NADPH cytochrome P450 reductase by the model sulfur mustard vesicant 2-chloroethyl ethyl sulfide is associated with increased production of reactive oxygen species

Joshua P. Gray, Vladimir Mishin, Diane E. Heck, Debra L. Laskin, Jeffrey D. Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

2010

Language:

english

File:

PDF, 807 KB

english, 2010